The Scope of Non-adherence

• In a meta-analysis of 569 studies of adherence to medical treatment recommendations between 1948 and 1998, DiMatteo (2004) found 24.8% average non-adherence across treatments, with a range of 4.6–100% non-adherence.

• Non-adherence rates differ among conditions, types of intervention/treatment, and methods of defining and measuring adherence.